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- What the Latest Research Is Telling Us About Women's Health | Bristol Menopause
< Back What the Latest Research Is Telling Us About Women's Health Exploring the latest research into menopause, hormones, and long-term health outcomes for women. Women's health research is undergoing a significant transformation. For many years, scientific focus centred largely on fertility, pregnancy, and childbirth, leaving relatively little attention to the health challenges women face during midlife and beyond. Today, that gap is closing. Recent research into menopause, hormone replacement therapy (HRT), cardiovascular health, bone health, cognitive function, and healthy ageing is reshaping clinical understanding of women's long-term wellbeing. Emerging evidence highlights the far-reaching impact of hormonal changes and supports a more holistic approach to menopause care. This article explores what the latest research tells us about women's health, how understanding of menopause has evolved, and what these developments mean for women seeking evidence-based treatment and support. Why Women's Health Research Has Changed One of the most important developments in recent years has been a broader understanding of the role of oestrogen throughout the body . Historically, oestrogen was viewed primarily as a reproductive hormone involved in menstruation, fertility, and pregnancy. However, researchers now recognise that oestrogen receptors are present throughout multiple body systems, including the: Brain Cardiovascular system Bones Skin Metabolic tissues As a result, declining hormone levels during perimenopause and menopause can affect much more than menstrual cycles. Symptoms and health outcomes may influence cardiovascular health, bone strength, cognitive function, metabolic wellbeing, skin health, and overall quality of life. Another key factor has been the reassessment of findings from the Women's Health Initiative (WHI) study published in the early 2000s. Initial interpretations led to widespread concern regarding HRT safety. Subsequent analyses demonstrated that many of the reported risks were applied too broadly, particularly to women who began treatment many years after menopause rather than during the menopausal transition. This re-evaluation has prompted renewed investment in menopause research and a substantial increase in high-quality studies examining the benefits and risks of modern hormone therapy. Understanding the Role of Hormones Beyond Reproduction Modern research confirms that hormones play a critical role in maintaining health throughout a woman's life. Oestrogen contributes to: Maintaining bone mineral density Supporting healthy blood vessel function Regulating cholesterol metabolism Supporting mood and emotional wellbeing Influencing cognitive processing and memory Preserving skin elasticity and collagen production When oestrogen levels decline during menopause, multiple physiological systems are affected simultaneously. This explains why many women experience menopause as a whole-body transition rather than simply the end of menstrual periods. For this reason, menopause is increasingly recognised as an endocrine event with systemic health implications , rather than solely a reproductive milestone. Healthcare professionals are now taking a broader approach to menopause assessment, considering factors such as cardiovascular risk, osteoporosis prevention, metabolic health, and cognitive wellbeing alongside symptom management. Latest Research on Menopause, HRT and Long-Term Health Cardiovascular Health Cardiovascular disease remains the leading cause of death among women worldwide, making this area of research particularly important. Recent evidence suggests that the timing of hormone therapy is a significant factor in cardiovascular outcomes. Studies indicate that women who begin HRT within ten years of menopause onset may experience cardiovascular benefits, whereas initiating treatment much later may not provide the same advantages and may increase certain risks. Research also suggests that transdermal HRT , including patches and gels, together with body-identical hormone formulations, may offer a more favourable cardiovascular profile compared with some older oral synthetic therapies. The growing emphasis is therefore not simply on whether HRT is used, but on choosing the most appropriate treatment type, dose, and route of administration. Dementia and Cognitive Health Concerns regarding dementia risk have often influenced decisions about menopause treatment. A major systematic review and meta-analysis published in The Lancet Healthy Longevity and commissioned by the World Health Organization analysed data from more than one million participants. Researchers found no convincing evidence that hormone therapy significantly increases or decreases dementia risk in postmenopausal women. For clinicians and patients, this provides reassurance and supports a personalised approach to treatment decisions. Hormone therapy should be prescribed based on symptom burden, individual health factors, and clinical need rather than expectations regarding future dementia prevention. Bone Health and Osteoporosis Prevention The protective effect of oestrogen on bone health remains one of the strongest evidence-based indications for HRT. Multiple studies continue to demonstrate that hormone therapy can: Preserve bone mineral density Reduce fracture risk Protect against osteoporosis after menopause Research comparing HRT with weight-bearing exercise found greater improvements in bone density among women using hormone therapy. However, exercise remains a critical component of osteoporosis prevention and is often recommended alongside treatment. For women at increased risk of osteoporosis, menopause presents an important opportunity to assess long-term bone health and preventative strategies. Metabolic Health and Weight Management Weight gain and changes in body composition are among the most common concerns reported during menopause. Emerging evidence suggests hormone therapy may support healthier fat distribution and metabolic function during the menopause transition. Researchers are increasingly exploring links between menopause, insulin sensitivity, body composition changes, and weight-management interventions. This is expected to become a major area of women's health research over the coming years, particularly as newer weight-management medications become more widely used. The Growing Evidence Supporting HRT Taken together, recent research presents a more balanced and reassuring picture of Hormone Replacement Therapy (HRT) . Current evidence suggests that appropriately prescribed HRT offers significant benefits for many women, including: Effective relief of menopausal symptoms Improved quality of life Bone protection Potential cardiovascular benefits when started at the appropriate stage Importantly, modern menopause care has moved beyond asking whether HRT is universally safe or unsafe. The focus is now on identifying: Which women are most likely to benefit When treatment should be started Which hormone formulations are most suitable How individual risks can be managed effectively HRT is not appropriate for every woman, but for many, it remains one of the most effective treatments available for menopause symptoms and long-term health protection. Why Personalised Menopause Care Matters Perhaps the strongest theme emerging from modern women's health research is the importance of individualised care. Factors influencing treatment decisions include: Age at menopause onset Family medical history Cardiovascular risk factors Bone health status Current medical conditions Symptom severity Lifestyle factors Personal treatment preferences Two women of the same age presenting with similar symptoms may require entirely different management plans. This is why specialist menopause consultations are increasingly valued. Comprehensive assessment allows treatment recommendations to be tailored to an individual's symptoms, health profile, and long-term wellbeing goals. At Bristol Menopause Clinic , this personalised approach ensures women receive evidence-based guidance that reflects both current research and their unique circumstances. The Future of Women's Health Research Several areas are expected to drive advances in menopause and women's health care over the next five years: 1. Metabolic Health and Weight Management Further research will examine how menopause, hormone therapy, and weight-management treatments interact to influence long-term health outcomes. 2. Cognitive Health Studies will continue exploring brain fog, memory changes, and cognitive function during perimenopause and menopause. 3. Non-Hormonal Menopause Treatments New treatment options, including neurokinin receptor antagonists, are providing effective alternatives for women who cannot or choose not to use HRT. 4. Personalised Risk Assessment Advances in genetics, digital health tools, and predictive medicine are expected to support increasingly tailored treatment recommendations. 5. Workplace Menopause Support Growing awareness of menopause in the workplace is driving research into occupational health, employee wellbeing, and employer responsibilities. Women's health research has advanced rapidly in recent years. Menopause is now recognised as a significant health transition that affects multiple body systems, not simply reproductive function. Current evidence increasingly supports the use of appropriately prescribed Hormone Replacement Therapy (HRT) as a safe and effective treatment for many women when considered within an individual risk-benefit framework. Most importantly, research continues to reinforce the value of personalised menopause care. By combining specialist clinical assessment with the latest evidence, women can make informed decisions about symptom management, bone health, cardiovascular wellbeing, and healthy ageing. If you are experiencing symptoms of perimenopause or menopause and would like personalised advice, Bristol Menopause Clinic offers specialist consultations tailored to your individual health needs and goals. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- How Do I Know If My Symptoms Are Due to Perimenopause? | Bristol Menopause
< Back How Do I Know If My Symptoms Are Due to Perimenopause? Many women find themselves wondering: Is this perimenopause? Or is something else going on? The challenge is that perimenopause symptoms can be subtle, intermittent, and wide-ranging. Many women find themselves wondering: Is this perimenopause? Or is something else going on? The challenge is that perimenopause symptoms can be subtle, intermittent, and wide-ranging . The hormonal transition leading up to menopause rarely follows a predictable pattern. Symptoms may appear gradually, fluctuate over time, or overlap with other common health conditions, making it difficult to identify the cause. In the UK, the average age of menopause is around 51 , although the normal range is between 45 and 55 . What is often less widely recognised is that perimenopause can begin several years before periods stop completely . Hormonal changes may start in the early to mid-40s, and sometimes even in the late 30s. As a result, many women experience symptoms earlier than they expect . Perimenopause Is Not Just About Hot Flushes When menopause is discussed, hot flushes and night sweats are often considered the defining symptoms. While they are common, they are not universal . Around 20% of women never experience hot flushes at all . Perimenopause affects far more than reproductive health. Oestrogen plays a role in multiple systems throughout the body , including the brain, joints, skin, cardiovascular system, and urogenital tissues. As hormone levels fluctuate, a wide range of symptoms can develop. Common perimenopause symptoms may include: Mood changes, anxiety, or irritability Low motivation or reduced resilience to stress Poor concentration or “brain fog” Disturbed sleep or insomnia Fatigue or reduced energy Joint aches, stiffness, or muscle pains Headaches or worsening migraines Hair thinning or dry skin Vaginal dryness or changes in libido Heart palpitations These symptoms can develop gradually or appear unexpectedly. Some women experience several symptoms together, while others notice only one or two. In many cases, they may not immediately resemble what people traditionally associate with menopause . Why Perimenopause Can Be Difficult to Diagnose One of the main reasons perimenopause is often overlooked is that many of its symptoms overlap with other common conditions. For example: Fatigue, low mood, and poor concentration may be mistaken for depression. Palpitations or anxiety may be attributed to stress. Hair thinning, weight changes, and tiredness may suggest thyroid dysfunction. Persistent fatigue or brain fog could indicate low iron levels. Joint pain may be dismissed as ageing or early arthritis. Because of this overlap, it is important not to jump to conclusions. Baseline blood tests , particularly for thyroid function and iron (ferritin) levels , can help rule out other causes and ensure nothing important is being missed. Another complexity is that perimenopause is driven by fluctuating hormone levels rather than a steady hormonal decline . Symptoms may improve for weeks and then return suddenly. This stop-start pattern can leave women questioning whether the symptoms are hormonal at all. Changes in Periods, But Not Always Missing Periods Changes in menstrual cycles can provide important clues, but they are not always straightforward. Perimenopause does not only cause missed periods . Other changes may occur first, including: Shorter menstrual cycles Heavier or lighter bleeding More irregular periods Worsening premenstrual symptoms (PMS) Some helpful questions to consider include: Has my cycle length or bleeding pattern changed significantly? Do my symptoms seem cyclical or linked to certain points in my cycle ? Are my symptoms more intense than would be expected from normal life stress ? However, identifying menstrual changes can be more difficult if you use hormonal contraception , as this alters bleeding patterns. It can also be challenging for women who have had a hysterectomy or endometrial ablation , as there may be no menstrual cycle to monitor. In these situations, clinicians rely more heavily on symptom history and overall clinical assessment . Perimenopause Is Usually a Clinical Diagnosis Perimenopause is primarily diagnosed based on symptoms and history , rather than hormone blood tests. Hormone levels fluctuate significantly during this stage of life, meaning that a single “normal” blood test result does not exclude perimenopause . Instead, clinicians consider the broader picture , including: Symptom patterns Menstrual history Sleep and stress levels Lifestyle factors Mental wellbeing Relevant blood tests where appropriate This holistic approach is important because perimenopause often occurs during a demanding stage of life. Many women are balancing careers, teenage children, ageing parents, and other significant pressures , all of which can influence health and wellbeing. Keeping a symptom diary can be extremely helpful. Tracking sleep, mood, headaches, anxiety, pain levels, and menstrual cycles may reveal patterns that would otherwise be missed. When a Trial of HRT May Be Appropriate If symptoms are significantly affecting quality of life, work, or relationships, treatment options should be considered . In some cases, a monitored trial of Hormone Replacement Therapy (HRT) can be helpful. Modern body-identical HRT , which uses hormones structurally identical to those produced by the body, has a favourable safety profile for most healthy women under 60 . For many women, a trial of HRT can be both diagnostic and therapeutic . If symptoms improve significantly with treatment, it strongly suggests that hormonal changes were contributing to the problem . Understanding Your Symptoms Perimenopause can be difficult to recognise because symptoms fluctuate, mimic other conditions, and do not always follow a predictable pattern . If you are experiencing persistent changes in your mood, sleep, energy levels, or menstrual cycle , it may be helpful to seek professional advice. A thorough assessment can help determine whether your symptoms are related to perimenopause, another health condition, or a combination of factors . Understanding what is happening in your body is often the first step toward finding the right support and treatment options . If you recognise several of these symptoms and they are affecting your daily life, it may be helpful to speak with a clinician experienced in menopause care. At the Bristol Menopause & Wellwoman Clinic , our specialists provide comprehensive assessments to help determine whether your symptoms may be related to perimenopause and discuss appropriate treatment options. If you would like support, you can book an initial consultation with one of our menopause specialists HERE References El Khoudary SR, Greendale G, Crawford SL, Avis NE, Brooks MM, Thurston RC, Karvonen-Gutierrez C, Waetjen LE, Matthews K. The menopause transition and women's health at midlife: a progress report from the Study of Women's Health Across the Nation (SWAN). Menopause. 2019 Oct;26(10):1213-1227. doi: 10.1097/GME.0000000000001424. PMID: 31568098; PMCID: PMC6784846 Avis NE, Crawford SL, Green R. Vasomotor Symptoms Across the Menopause Transition: Differences Among Women. Obstet Gynecol Clin North Am. 2018 Dec;45(4):629-640. doi: 10.1016/j.ogc.2018.07.005. Epub 2018 Oct 25. PMID: 30401547; PMCID: PMC6226273. Santoro N. Perimenopause: From Research to Practice. J Womens Health (Larchmt). 2016 Apr;25(4):332-9. doi: 10.1089/jwh.2015.5556. Epub 2015 Dec 10. PMID: 26653408; PMCID: PMC4834516. Harlow SD, Paramsothy P. Menstruation and the menopausal transition. Obstet Gynecol Clin North Am. 2011 Sep;38(3):595-607. doi: 10.1016/j.ogc.2011.05.010. PMID: 21961722; PMCID: PMC3232023. L'Hermite M. HRT optimization, using transdermal estradiol plus micronized progesterone, a safer HRT. Climacteric. 2013 Aug;16 Suppl 1:44-53. doi: 10.3109/13697137.2013.808563. PMID: 23848491. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Platinum Wellwoman Check | Bristol Menopause
Blood Tests Basic Hormone Profile ✔️Oestradiol ✔️Testosterone ✔️Sex Hormone Binding Globulin (SHBG) £110 Book here Ultimate Hormone Profile Oestradiol Test ✔️Follicle Stimulating Hormone (FSH) ✔️Luteinising Hormone (LH) ✔️Progesterone ✔️Prolactin ✔️Testosterone ✔️Sex Hormone Binding Globulin (SHBG) £125 Book here Ultimate WellWoman Blood Test ✔️Oestradiol ✔️Progesterone ✔️Luteinising Hormone (LH) ✔️Follicle Stimulating Hormone (FSH) ✔️Testosterone ✔️Sex Hormone Binding Globulin (SHBG) ✔️Prolactin ✔️Insulin Levels ✔️Cortisol ✔️DHEA Sulphate – A precursor to both oestrogen and testosterone, important for energy, mood, and stress resilience. ✔️Vitamin D 25(OH) – Essential for bone health, immune system function, and mood regulation. £290 Book here Fertility Blood Test ✔️ Thyroid Health ✔️ Hormone Health ✔️ Vitamin D ✔️ Full Blood Count ✔️ Iron Status ✔️ Liver Health ✔️ Diabetes Health ✔️ Stress ✔️ Heart Health ✔️ Kidney Health ✔️ Infection & Inflammation £180 Book here Important Note About Hormone Replacement Therapy (HRT) Gels Please Do Not Apply Any HRT Gels Until After Your Blood Test.
- Let’s talk honestly about HRT and breast cancer | Bristol Menopause
< Back Let’s talk honestly about HRT and breast cancer HRT There’s a lot of fear flying around online right now, especially after recent headlines, so let’s set the record straight with facts, not fear. Here’s what you need to know HRT (Hormone Replacement Therapy) is the most effective treatment for menopausal symptoms, hot flushes, night sweats, low mood, poor sleep, joint pain, and vaginal dryness. Does HRT cause breast cancer? For most women , the answer is no, it doesn’t “cause” breast cancer . There can be a small increase in risk with combined HRT (oestrogen + progesterone), especially if used for longer than 5 years after the age of 51, this means that breast cancer risk is not thought to increase until 51 for HRT users and then continue to be low risk for 5 years. Oestrogen-only HRT (used if you’ve had a hysterectomy) does not increase risk and may even slightly lower it. When you stop HRT , any small extra risk goes down again over time. Remember: The absolute risk is small (around 5 extra cases per 1,000 women taking combined HRT for 5 years). Your personal risk depends on family history, weight, alcohol intake, and other factors not just HRT. The benefits of HRT, better sleep, mood, energy, bone and heart health can be life-changing. It’s about balance, not blanket fear. Every woman’s situation is different, and HRT should always be discussed and tailored individually. If you’re unsure or concerned by what you’ve read, please talk to a menopause specialist rather than relying on social media headlines. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Doctor’s Quick Tip: Beat Brain Fog & Stay Sharp During Menopause! | Bristol Menopause
< Back Doctor’s Quick Tip: Beat Brain Fog & Stay Sharp During Menopause! Alternative Therapies, Diet, Exercise, HRT, Managing Symptoms, Mental Health, Self-Care, Wellbeing Ever walked into a room and completely forgotten why? Or found yourself searching for your glasses… only to realise they’re on your head? If menopause has you feeling forgetful, distracted, or mentally foggy, you’re NOT alone. Brain fog during menopause is real , and it happens due to hormonal shifts —mainly the drop in oestrogen , which plays a key role in memory, focus, and mental clarity. But the good news? There are natural ways to boost your brainpower and feel sharper again! Why Does Menopause Cause Brain Fog? During perimenopause and menopause, oestrogen levels drop , which can lead to: Forgetfulness & trouble concentrating Mental fatigue & slow thinking Difficulty finding words ( "Wait, what was I saying?" ) Feeling overwhelmed or distracted Oestrogen helps regulate neurotransmitters like serotonin and dopamine , which keep your brain functioning at its best. Without it, your mental sharpness can take a hit—but don’t worry, you can take control! 5 Simple Ways to Beat Brain Fog! Hydrate, Hydrate, Hydrate! Your brain is 75% water , and even slight dehydration can cause brain fog. Aim for 8-10 glasses of water a day to keep your mind clear and sharp! Fuel Your Brain with the Right Foods What you eat directly affects your memory and focus ! Try adding: Healthy fats – Avocados, nuts, olive oil, and oily fish boost brain function Leafy greens – Spinach, kale, and broccoli are packed with brain-protecting antioxidants Berries – Blueberries and blackberries help improve memory and fight cognitive decline Dark chocolate – Yes, really! A little dark chocolate (70% cacao or higher) can enhance focus Avoid: Processed sugars, excess caffeine, and alcohol—they can make brain fog worse! Move Your Body to Sharpen Your Mind 🏃♀️ Exercise isn’t just for your body—it’s for your brain too! Yoga & meditation – Reduces stress & clears your mind Daily walks – Even 20 minutes improves brain function Strength training – Increases oxygen flow to the brain Regular movement boosts blood flow and releases endorphins , helping to clear mental fog! Prioritise Quality Sleep Brain fog gets worse when you’re sleep-deprived! Try this: Stick to a bedtime routine – Aim for 7-9 hours of sleep Limit screens before bed – Blue light disrupts melatonin production Keep your bedroom cool – Ideal temp = 65°F (18°C) for deep sleep Bonus Tip: Try magnesium or chamomile tea before bed for better relaxation! Train Your Brain Just like your muscles, your brain needs exercise too! Puzzles & word games – Keep your memory sharp Read daily – Stimulates brain activity Listen to music – Certain tunes improve focus & cognition Pro Tip: Learning something new—like a language, instrument, or hobby—keeps your brain active & engaged as you age! The Bottom Line: Brain Fog Isn’t Permanent! With the right hydration, nutrition, movement, sleep, and mental exercises , you can take control of menopause brain fog and feel mentally sharp again! Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Menopause and Brain Health: What Every Woman Should Know | Bristol Menopause
< Back Menopause and Brain Health: What Every Woman Should Know Brain fog. Forgetfulness. Difficulty concentrating. Mood swings. These are some of the most common and frustrating symptoms women report during menopause. For many, the changes feel frightening. Women worry about early dementia or losing their edge at work. Yet brain health in menopause is rarely discussed openly. Why Does Menopause Affect the Brain? Oestrogen plays a crucial role in brain function. It influences: Neurotransmitters like serotonin, dopamine, and acetylcholine. Blood flow to the brain. Protection of neurons against inflammation and oxidative stress. When oestrogen levels decline, women may experience memory lapses, poor sleep, low mood, and changes in cognitive performance. Is It Dementia? The good news: for most women, menopause brain fog is temporary . Studies show that memory and concentration often improve after the menopausal transition. But there is a long-term connection. After menopause, women face a higher lifetime risk of Alzheimer’s disease and other dementias compared to men. What Can Women Do to Protect Brain Health? Exercise regularly — physical activity increases blood flow and stimulates new brain cells. Prioritise sleep — poor sleep worsens memory and mood. Eat a Mediterranean-style diet rich in vegetables, whole grains, fish, and healthy fats. Stay mentally active — learning, reading, problem-solving keep neural connections strong. Manage stress — chronic stress accelerates cognitive decline. Consider HRT — for some women, starting HRT around the time of menopause may support memory and mood, though evidence is still evolving. Menopause is a brain health milestone as much as a hormonal one. By recognising the connection and taking proactive steps, women can support their memory, mood, and long-term cognitive resilience. Talk to a specialist at Bristol Menopause Clinic about protecting your brain health during menopause and beyond. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Hormone Profile | Bristol Menopause
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- Why Removing Patch Glue Properly Matters More Than You Think | Bristol Menopause
< Back Why Removing Patch Glue Properly Matters More Than You Think Why gentle adhesive removal matters for menopausal skin, patch performance and everyday confidence. For the many women who manage their menopause with HRT patches, there is a small, sticky frustration that rarely gets talked about, the grey residue left behind on the skin at every change. It is easy to dismiss as a minor annoyance. But how we deal with it matters more than most of us realise, for our skin, for our next patch, and even for how we feel about ourselves. I am Amy, founder of Nudi Spray , and I have spent a lot of time thinking about something most people never give a second thought to, and that is patch glue. What began as my own irritation with sticky marks turned into a bit of an education in skin, adhesives and menopause. So I wanted to share why this small daily ritual deserves a little more care than we tend to give it. Menopausal skin is not the skin it used to be To understand why residue matters, we first have to understand the landscape it is sitting on. Our skin is an oestrogen sensitive organ, and as oestrogen declines through perimenopause and menopause, the skin changes significantly, and faster than ordinary ageing alone would cause. In the first five years after menopause, skin can lose up to 30 per cent of its collagen, the protein that gives it strength and springiness. At the same time, the skin's protective barrier weakens. It produces fewer of the ceramides and natural oils that lock moisture in, so it becomes drier, thinner, more easily irritated and slower to heal. Many women notice their skin suddenly feels tight, reactive, or sensitive to products it happily tolerated for years. This is not imagination, it is measurable, and it is hormonal. All of which means the skin we are removing patch adhesive from is more fragile and less resilient than it once was. What might have been harmless in our thirties can cause real irritation now. Why leftover glue is more than a cosmetic nuisance There are a few good reasons to take residue seriously, rather than just living with it or scrubbing it away. It can affect your next patch This is the practical one. A build up of old adhesive on the skin can stop your next patch sticking properly. And a patch that lifts at the edges or does not adhere well may not deliver your hormones as reliably as one applied to clean skin. So keeping the skin clean between patches is not vanity, it genuinely supports your treatment working as it should. Harsh removal damages the skin barrier When faced with stubborn residue, the instinct is to scrub, or to reach for whatever is in the bathroom cabinet, rubbing alcohol, nail polish remover, baby oil. The trouble is that mechanical scrubbing creates friction on the stratum corneum, the skin's outermost protective layer, while solvents like alcohol and acetone strip it of its natural oils. On already thinning, barrier compromised menopausal skin, this can lead to redness, dryness, small rashes, and over time, increased sensitivity and slower healing. Ironically, the harder we try to get skin clean, the more we can damage it. The bit nobody mentions, how it makes us feel There is a psychological side to this too, and it deserves saying out loud. Menopause can already chip away at how comfortable we feel in our own skin. Adding visible grey marks, sometimes several at once from rotating patches, can feel like one more small indignity. Women tell me they feel self conscious in a swimming costume, at the gym, or simply getting undressed. It is a tiny thing on paper, but these tiny things accumulate, and feeling clean and cared for in your own body matters for your confidence and wellbeing. Removing that daily reminder, gently, can be a genuine little act of self kindness at a time when those count for a lot. How to look after your skin at every patch change The good news is that caring for the skin under and around your patch is simple. Remove residue gently rather than scrubbing, and avoid harsh solvents like alcohol and acetone, which do more harm than good on menopausal skin. Rotate your patch to a slightly different spot each time, giving each area a rest to prevent repeated irritation. Apply patches to clean, dry skin, free of lotions and oils, so they grip well and deliver reliably. And if your skin does become sore, soothe it with a gentle, fragrance free moisturiser, and see your GP or pharmacist if irritation persists. This is the thinking behind what I created. Nudi Spray gently lifts away patch adhesive in seconds, without scrubbing or harsh chemicals, and it is enriched with vitamin E to leave the skin soothed rather than stripped. But whatever method you use, the principle is the same, be as kind to this skin as it now needs you to be. A small ritual worth getting right HRT is a wonderful thing, and patches are a brilliant way to take it. But the little routine around them, the removing, the cleaning, the reapplying, is worth doing with a bit of care, especially now that our skin asks more of us. It protects your skin's health, helps your treatment work as it should, and gives you one less thing to feel self conscious about. And in menopause, the small kindnesses we show ourselves really do add up. About the author. Amy is the founder of Nudi Spray, a gentle adhesive remover created for women who use HRT patches. You can find out more at nudispray.com . This article is for general information and is not medical advice. Always follow the instructions provided with your own HRT patches, and speak to your GP or pharmacist about any skin concerns or questions about your treatment. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Understanding Perimenopause: Why Your Body Feels Different | Bristol Menopause
< Back Understanding Perimenopause: Why Your Body Feels Different If you're in your 40s and suddenly feeling like a stranger in your own body, you're not alone. Perimenopause- the transitional phase before menopause - affects every woman differently, but the confusion and frustration are universal. What's Actually Happening? Perimenopause typically begins in your 40s, though it can start earlier. During this time, your ovaries gradually produce less oestrogen, but it's not a steady decline. Hormone levels fluctuate wildly, which explains why symptoms can vary so dramatically from week to week. This phase can last anywhere from a few months to over a decade, with an average duration of four to eight years. It officially ends when you've gone 12 consecutive months without a period—that's menopause. The Symptoms No One Warned You About Yes, hot flushes and irregular periods are common. But perimenopause brings a constellation of symptoms that many women don't recognize as hormone-related: Brain fog and memory issues - Forgetting words mid-sentence or walking into rooms and forgetting why isn't early dementia; it's often perimenopausal brain fog. Oestrogen plays a crucial role in cognitive function, and fluctuating levels can affect concentration and memory. Anxiety and mood changes - That sudden sense of dread or irritability that seems to come from nowhere? Declining oestrogen affects neurotransmitters like serotonin and dopamine, which regulate mood. Sleep disruption - Even without night sweats, many women experience insomnia during perimenopause. You might fall asleep easily but wake at 3am with your mind racing. Changes in body composition - Despite eating the same diet, you might notice weight creeping on around your middle. Oestrogen influences how and where your body stores fat. Joint pain and muscle aches - Oestrogen has anti-inflammatory properties, so declining levels can lead to increased inflammation and discomfort. Why It Matters Too many women suffer through perimenopause believing these symptoms are just "part of aging" or that nothing can be done. The truth is quite different. Understanding what's happening in your body is the first step toward feeling like yourself again. Untreated perimenopausal symptoms can significantly impact quality of life, affecting relationships, work performance, and mental wellbeing. There's also emerging evidence that the menopausal transition represents a critical window for long-term health, particularly regarding cardiovascular and bone health. What Can Help? The good news is that effective treatments exist. Hormone Replacement Therapy (HRT) remains the gold standard treatment for perimenopausal symptoms. Modern body-identical HRT has an excellent safety profile for most women and can dramatically improve quality of life. Beyond HRT, lifestyle modifications can make a real difference: Regular exercise helps with mood, sleep, and weight management A Mediterranean-style diet supports overall health Stress management techniques like mindfulness can reduce symptom severity Limiting alcohol and caffeine may help with sleep and hot flushes You Deserve Support If you're experiencing perimenopausal symptoms, you don't have to struggle through this alone. A menopause specialist can provide comprehensive assessment, discuss treatment options suited to your individual needs, and help you navigate this transition with confidence. At Bristol Menopause Clinic , we're British Menopause Society accredited and specialise in providing evidence-based, personalised care for women at every stage of their menopause journey. Whether you're just starting to notice changes or have been struggling with symptoms for years, we're here to help you feel like yourself again. Remember: perimenopause is a natural transition, but suffering through it isn't. You deserve to feel well, think clearly, and enjoy this phase of your life. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Are GPs and Patients Missing the Menopause Link? A New Study Explores Mental Health Consultations in Perimenopause | Bristol Menopause
< Back Are GPs and Patients Missing the Menopause Link? A New Study Explores Mental Health Consultations in Perimenopause HRT, Menopause Advice, Perimenopause At Bristol Menopause & Wellwoman Clinic, we are proud to share important new research led by our Clinical Lead, Dr Jo Burgin, alongside a team of three other medical professionals, exploring a crucial but often overlooked area of women’s health: the link between mental health and perimenopause in general practice consultations. Why This Research Matters Perimenopause, the transitional years before menopause, is a time of significant hormonal change. For many women, this period brings not only physical symptoms like hot flushes and irregular periods, but also profound mood changes, including anxiety, low mood, and irritability. Yet, these mental health symptoms are frequently misattributed or missed altogether. Dr Burgin’s study, "Mental health consultations during the perimenopausal age range – Are GPs and patients on the same page?" , investigates this communication gap between women and their GPs. Her findings shed light on the missed opportunities and challenges that many women face when seeking help. What the Study Found This qualitative research involved interviews with 18 women aged 45–55 and 11 GPs. All women had visited their GP with a mental health concern in the past six months. The aim? To understand how these consultations unfolded – and whether the perimenopause was considered as a possible contributing factor. Key findings include: Women often don’t connect the dots : Many participants were unsure whether their mood symptoms could be linked to perimenopause. Some felt uncertain, others embarrassed to bring it up. GPs aren’t always asking : While some GPs recognised the potential link between hormone changes and mental health, approaches varied widely. Others admitted to gaps in training or confidence in addressing menopause-related issues. Stigma and time pressures are barriers : Both patients and GPs reported that stigma, especially around menopause and mental health, along with limited appointment time, made these conversations more difficult. What Needs to Change The conclusion of the study is clear: to improve mental health outcomes for women in midlife, we must strengthen both GP training and patient education around perimenopause. Women need to feel confident raising concerns, and GPs need the tools to recognise and manage perimenopausal symptoms effectively. What This Means for You If you’re in your 40s or 50s and experiencing new or worsening mental health symptoms, it’s worth asking whether hormonal changes might be playing a role. Mood swings, anxiety, irritability, and even depression can be part of perimenopause – and there are many ways to help, from lifestyle changes to HRT. At Bristol Menopause & Wellwoman Clinic, we believe in taking women’s mental health seriously. Our team offers comprehensive, personalised care that looks at the whole picture – including your hormones. Full research paper can be read here Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us
- Testosterone Package - 10% saving | Bristol Menopause
< Back Testosterone Package - 10% saving £540 Take Control of Your Hormonal Health with Our Testosterone Support Package – £540 10% saving when you book the full Testosterone Support Package. Our comprehensive package is designed for new patients, providing expert care, accurate hormone assessment, and ongoing support. What’s Included in the Testosterone Support Package: Initial 45-Minute Consultation In-depth consultation with a specialist Doctor: discuss your symptoms, concerns, and health history. Personalised health plan: tailored lifestyle, nutrition, and treatment options to optimise testosterone levels. Hormone Blood Test Panel (included with your first appointment only): full assessment of testosterone oestradiol and SHBG. Private prescribing (if needed): appropriate treatment options provided by your specialist. Letter to your GP: summary of consultation, results, and treatment plan for continuity of care. Review Appointment (3months post commencing testosterone) Progress review: assess results, symptoms, and wellbeing with your specialist. Hormone Blood Test Panel (included with your first appointment only): full assessment of testosterone oestradiol and SHBG. Treatment adjustments (if required): ensure your plan evolves with your needs. Ongoing support and advice: guidance on managing new symptoms or concerns. Private prescribing (if required): further prescriptions can be issued. Letter to your GP: update on progress and any treatment changes. Benefits of Booking the Testosterone Support Package: Expert care every step of the way – from your first consultation to your review. Tailored, ongoing support – treatment plan evolves with your needs. Cost-effective package – £540 includes consultation, two hormone panels, and review appointment. Personalised approach – designed around your unique hormonal health and goals. Confidence in your journey – with expert guidance to help you feel your best. Book Your Testosterone Support Package Today Take charge of your hormonal health and feel supported every step of the way. Book Here Please note: In line with our policy, you are unable to book with a doctor who is your registered GP or a GP at the practice where you are currently registered. This includes Dr Jo Burgin (Bridgeview Medical Practice) and Dr Danielle Calandrini (Newbridge Surgery). Thank you for your understanding. Previous Next
- Iron Deficiency in Midlife Women: What Works, What Does Not, and Why | Bristol Menopause
< Back Iron Deficiency in Midlife Women: What Works, What Does Not, and Why Alternative Therapies Understanding Ferritin, Fatigue, Brain Fog, Hair Loss, and Why “Normal” Blood Tests Are Not Always Optimal Iron deficiency is one of the most overlooked contributors to fatigue, brain fog, low mood, poor concentration, hair thinning, and reduced exercise tolerance in women during perimenopause and menopause. Yet despite how common it is, many women are told their blood tests are “normal” when, clinically, their iron stores are far from optimal. At Bristol Menopause Clinic , we frequently see women whose menopausal symptoms only partially improve with HRT because an underlying iron deficiency has never been properly identified or treated. The reality is simple: treatment is not just about taking iron. The type of iron, how it is taken, what is preventing absorption, and understanding the root cause all matter enormously. Why Iron Deficiency Is So Common in Midlife Women Iron depletion often develops gradually over years. Heavy menstrual bleeding, restrictive dieting, gastrointestinal conditions, thyroid disease, stress-related digestive issues, and long-term medication use can all contribute. The challenge is that the symptoms overlap significantly with menopause itself: Fatigue Brain fog Poor concentration Anxiety or low mood Hair thinning Reduced stamina Poor sleep Palpitations Restless legs As a result, many women assume hormones are the only explanation. Treatment Options: What Actually Works 1. Iron Supplementation Iron supplementation can be highly effective — but the form of iron matters considerably. Many women are prescribed traditional ferrous salts, which are inexpensive and clinically effective, but often poorly tolerated. Gastrointestinal side effects are one of the biggest reasons women stop treatment too early. Form Typical Dose Tolerability & Clinical Notes Ferrous sulphate 200mg twice daily Effective but commonly causes constipation, nausea, bloating, and abdominal discomfort Ferrous fumarate 210mg twice daily Similar efficacy to ferrous sulphate; slightly better tolerated in some women Iron bisglycinate 25–50mg elemental iron Chelated form with superior absorption and significantly fewer gastrointestinal side effects Liquid iron As directed Useful for women unable to tolerate tablets; often gentler on digestion IV iron infusion Clinician-administered Reserved for severe deficiency, malabsorption, or failure of oral therapy Alternate Day Dosing: A More Effective Strategy Emerging evidence suggests that alternate-day dosing may actually improve iron absorption compared with daily supplementation. This relates to the hormone hepcidin, which rises after taking iron and temporarily blocks absorption for up to 24 hours. Taking iron every other day may therefore improve overall uptake while reducing gastrointestinal side effects. For many women, this approach is both more effective and easier to maintain long term. Optimising Iron Absorption Iron is one of the most absorption-sensitive nutrients in human physiology. Two women taking the same supplement can absorb vastly different amounts depending on timing, medications, and dietary habits. Take Iron with Vitamin C Vitamin C improves the absorption of non-haem iron by converting it into a more absorbable form. Helpful combinations include: Iron with kiwi fruit Iron with berries Iron with citrus juice Iron with tomatoes or peppers Avoid Tea and Coffee Around Supplement Timing Tea and coffee contain tannins that significantly reduce iron absorption. Even herbal teas such as peppermint may interfere. Avoid these for at least one hour either side of taking iron. Separate Iron from Calcium Calcium competes directly with iron absorption. Avoid taking iron alongside: Milk Cheese Calcium supplements Calcium-fortified products Ideally, allow a two-hour gap. Thyroid Medication Timing Matters Iron can reduce the absorption of levothyroxine. Women taking thyroid medication should separate iron and levothyroxine by at least two hours. Cooking in Cast Iron Cooking acidic foods such as tomato sauces or stews in cast-iron cookware can meaningfully increase the iron content of meals, a simple but clinically useful habit. Dietary Optimisation Diet alone is rarely enough to correct significant iron depletion, but it plays an essential role in long-term maintenance. Haem Iron: Best Absorbed Haem iron is absorbed efficiently regardless of other dietary factors. Best sources include: Red meat Lamb Dark poultry meat Shellfish Clams Oysters Liver (avoid during pregnancy) Non-Haem Iron: More Difficult to Absorb Plant-based iron sources are less efficiently absorbed and highly dependent on what they are eaten with. Sources include: Lentils Chickpeas Kidney beans Tofu Pumpkin seeds Quinoa Fortified cereals Dark leafy greens Improving Plant-Based Iron Absorption Pairing plant iron with vitamin C-rich foods significantly improves absorption. Examples include: Lemon juice on spinach Tomatoes with lentils Red peppers in bean dishes Citrus dressings on salads For vegetarian and vegan women with depleted ferritin levels, supplementation is often clinically necessary rather than optional. Addressing the Underlying Cause Correcting ferritin without understanding why it became depleted often leads to recurrence. Common reversible causes include: Heavy Menstrual Bleeding Perimenopausal bleeding changes are one of the most common contributors to iron depletion. Appropriate hormonal treatment, including HRT, may significantly reduce ongoing losses. Coeliac Disease Undiagnosed coeliac disease can impair iron absorption even in women with an otherwise healthy diet. Women with persistently low ferritin despite supplementation should be screened. Helicobacter pylori Infection This common stomach bacteria can interfere with iron absorption. Eradication therapy may restore normal absorption. Proton Pump Inhibitors (PPIs) Long-term reflux medications reduce stomach acid, impairing iron absorption. Medication reviews are often worthwhile. Thyroid Disease Hypothyroidism is associated with impaired iron absorption and reduced energy metabolism. Treating thyroid dysfunction frequently improves iron status. Monitoring Your Response Iron replacement is not a quick fix. Expect a 3–6 Month Process Ferritin restoration takes time. Many women feel discouraged when they do not notice immediate improvement. Meaningful replenishment usually takes: Around 3 months for early improvement Up to 6 months or longer for full restoration Recheck Blood Tests Repeat testing should ideally include: Ferritin Full blood count CRP Vitamin B12 Folate Monitoring ensures levels are improving appropriately and helps guide maintenance therapy. Optimal Ferritin Matters Many laboratories classify ferritin levels around 15–30 µg/L as “normal”. Clinically, however, many symptomatic women feel significantly better when ferritin reaches: 70–100 µg/L Normal is not always optimal. The Menopause Connection Iron deficiency and menopause frequently coexist — and they often amplify one another. In clinic, we commonly see women whose HRT has improved symptoms partially, but who continue to experience: Fatigue Brain fog Hair shedding Low resilience Reduced exercise tolerance When ferritin is investigated and corrected appropriately, the improvement can be significant. Equally, effective menopause management may help preserve iron stores by reducing heavy or erratic bleeding patterns. Treating hormones without addressing nutritional status often produces incomplete results. The best outcomes come from looking at the whole picture. When Should You Seek Further Investigation? If you are experiencing persistent: Fatigue Brain fog Hair loss Poor recovery Low mood Symptoms despite otherwise healthy lifestyle habits …it is worth investigating iron properly. Recommended blood tests include: Serum ferritin Full blood count Active B12 Folate CRP Thyroid function Vitamin D If ferritin is below 70 µg/L and symptoms are present, treatment may still be clinically appropriate, even if you are not anaemic. “Normal” is not always the same as optimal and you deserve to know the difference. Get in Touch If you would like a personal Wellwoman Check, or are suffering from any of the symptoms of the menopause and would like to learn more, please head to our contact page to book an appointment. You'll be so glad you did! Contact Us

