Hormone Replacement Therapy (HRT) in the form of transdermal oestrogen gels, creams and sprays is a highly effective and commonly prescribed treatment for managing menopausal symptoms. These preparations are absorbed through the skin and provide a convenient alternative to oral therapy.

However, an important and often overlooked consideration is the potential for unintentional transfer of oestrogen to others, particularly children and pets.

Can HRT Be Transferred to Others?

Yes, if the application site is touched or licked before the product has fully dried, small amounts of oestrogen can transfer to another person or animal.

While the amount transferred is typically low, repeated exposure over time may lead to hormonal effects, particularly in more vulnerable individuals such as young children and animals.

Reported effects may include:

• In children: breast or nipple changes, or signs of early puberty

• In pets: behavioural changes (such as signs resembling being “in heat”), or changes to coat or skin

Although these situations are uncommon, they are preventable with appropriate precautions.

How to Minimise the Risk

Simple, practical steps can significantly reduce the likelihood of transfer:

• Apply the product only to the recommended area and avoid spreading beyond this

• Allow the product to dry fully before close contact (ideally around 60 minutes)

• Wash your hands thoroughly with soap and water after application

• Cover the application site with clothing before physical contact, such as cuddling children or allowing pets onto your lap

• Avoid allowing pets to lick the application area

These measures are particularly important in the period immediately after application, when the risk of transfer is highest.

What Should You Do If You Are Concerned?

If you suspect that a child or pet may have had repeated exposure and you notice any physical or behavioural changes, it is important to seek advice:

• Contact your GP or paediatrician for children

• Contact your veterinary surgeon for pets

Early assessment can help provide reassurance and guide any necessary next steps.

Do These Risks Apply to All Forms of HRT?

It is important to note that this risk does not apply in the same way to oestrogen patches.

Oestrogen patches are sealed delivery systems, meaning the hormone is contained within the patch and delivered directly through the skin. When used correctly and kept intact, they are not thought to transfer oestrogen through skin contact, such as cuddling or lap-sitting.

However, general safety precautions still apply:

• Keep both new and used patches out of reach of children and pets

• Fold used patches in half (adhesive sides together) before safe disposal

  
  

Transdermal HRT remains a safe and effective treatment when used correctly. Awareness of this small but important risk allows you to take simple steps to protect those around you.

Always:

• Follow the instructions provided in your HRT patient information leaflet

• Speak to your prescriber or pharmacist if you have any questions or concerns

  
  

At Bristol Menopause Clinic, we are committed to providing clear, evidence-based guidance to support safe and effective menopause care. If you would like to review your HRT or discuss the most suitable options for you, our team is here to help.